(Download) "Evolution of Translational Omics" by Christine M. Micheel, Committee on the Review of Omics-Based Tests for Predicting Patient Outcomes in Clinical Trials, Board on Health Care Services, Board on Health Sciences Policy & Institute of Medicine # eBook PDF Kindle ePub Free
eBook details
- Title: Evolution of Translational Omics
- Author : Christine M. Micheel, Committee on the Review of Omics-Based Tests for Predicting Patient Outcomes in Clinical Trials, Board on Health Care Services, Board on Health Sciences Policy & Institute of Medicine
- Release Date : January 13, 2012
- Genre: Science & Nature,Books,Life Sciences,Professional & Technical,Medical,
- Pages : * pages
- Size : 1941 KB
Description
Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.
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