[DOWNLOAD] "Evolution-adjusted Tumor Pathophysiology:" by Albrecht Reichle * Book PDF Kindle ePub Free

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eBook details

• Title: Evolution-adjusted Tumor Pathophysiology:
• Author : Albrecht Reichle
• Release Date : January 01, 2013
• Genre: Medical,Books,Professional & Technical,Science & Nature,Life Sciences,
• Pages : * pages
• Size : 9376 KB

Description

Combined modularized therapies for metastatic cancer are pointing to central problems of communication among ‘systems participators’. A communication theory explains 'social engineering', endogenously induced or by implementing non-normative boundary conditions. Evolution-adjusted tumor pathophysiology is borne by an evolution theory, which contrasts narrative evolution histories. The tool of rationalizations constituting the tumor's normativity (inflammation, immune response etc.) represents the non-genomic counterpart of the tumor genome and should be additionally assessed during tumor staging. Evolution-adjusted tumor pathophysiology allows implementing applied systems biology, a novel clinical and pharmaceutical technology for bioengineering tumor response and personalizing tumor therapy. Combined modularized therapy, evolution-adjusted tumor pathophysiology, and ‘universal’ biomarkers concertedly address genetically based tumor heterogeneity.

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